Journal for Advanced Instrumentation in Science (JAIS) is a new peer-reviewed, open access journal specialized in advanced instrumentation both for experimental research in basic science and for technological developments and applications in different environmental and bioengineering fields. JAIS aims to span over a large variety of items, from new generation of gas and silicon detectors for particle and astroparticle physics to innovative sensors for environmental monitoring, and medical diagnostic, also with laser driven technologies. Since important role in the instrumentation development is related to the readout electronics and data processing, JAIS also intends to offer its platform to review frontier achievements in the area of microelectronics and machine learning algorithms. The goal is to provide the community of physicists and engineers involved in the above mentioned fields with a platform to publish informative summaries of important findings.